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| pyogenic granuloma (686.1) |   Pyogenic Granuloma (Granuloma Telangiectaticum) A scarlet, brown, or blue-black vascular nodule composed of proliferating capillaries in an edematous stroma (see Plate 125-5-1). The term pyogenic granuloma is a misnomer: The lesion, composed of granulation tissue, is neither of bacterial origin nor a true granuloma. It develops rapidly, often at the site of recent injury, and probably represents a vascular and fibrous response to injury. There is no sex or age predilection. The overlying epidermis is thin, and the lesion tends to be friable, bleeds easily, and does not blanch on pressure (see Plate 125-5-2). The base may be pedunculated and surrounded by a collarette of epidermis. The lesions occasionally resemble and must be differentiated from melanomas or other malignant tumors. During pregnancy, pyogenic granulomas may become large and exuberant--eg, gingival pregnancy tumors, or telangiectatic epulis. Treatment consists of removal by excision or curettage and electrodesiccation, but the lesions may recur. {The Merck Manual of Diagnosis and Therapy; Section 10. Dermatologic Disorders; Chapter 125. Benign Tumors: (http://www.merck.com/pubs/mmanual/section10/chapter125/125g.htm) |
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